Low-Dose Radiation Therapy (LDRT) for Osteoarthritis Pain Relief

LDRT is a non-invasive, low-radiation-dose treatment that uses very small doses of radiation to reduce inflammation and relieve pain in arthritic joints. This website provides comprehensive information about LDRT, including how it works, clinical evidence, and a directory of providers across the United States.

What does LDRT stand for?

LDRT stands for low-dose radiation therapy. For osteoarthritis, it uses very small, targeted radiation doses to help calm inflammation in a painful joint. The total dose is roughly one twentieth or less of a typical cancer radiation dose and is usually delivered over about six short visits.

Key Benefits of LDRT

• Painless, non-invasive treatment — no surgery, no needles
• Each session takes only a few minutes
• Reported response rates range from roughly 60% to 90% across published studies, per the 2026 American Radium Society Appropriate Use Criteria and DEGRO. Response varies by study design, joint treated, and follow-up duration.
• When it helps, effects can last 6–24 months or longer from a single course
• Treatment can be repeated if needed

Learn More

• What Is LDRT? How It Works & What to Expect
• Clinical Evidence & Research Studies
• LDRT for Knee Osteoarthritis
• Find an LDRT Provider Near You
• Frequently Asked Questions
• For Healthcare Providers
• About Us
• Editorial Policy

Medically reviewed by: Robert Warren Floyd, M.D., Ph.D. — Resident Physician, Radiation Oncology, The University of Texas MD Anderson Cancer Center. Last reviewed: September 8, 2026. Independent personal project — not affiliated with or endorsed by MD Anderson Cancer Center. Funding & independence disclosure.

This content is for education only and is not medical advice. Always consult a qualified healthcare provider for diagnosis and treatment decisions.